刘石惠，博士，副教授，硕士生导师，“创新嘉兴·精英引领计划”青年人才，嘉兴大学勤慎青年学者。2019年毕业于华东理工大学药学专业，获博士学位，同年入职嘉兴大学，2019年7月受聘于嘉兴大学医学院，从事药物化学教学和科研工作。现主持国家自然科学基金青年基金项目1项，浙江省自然科学基金探索项目1项，嘉兴市科技计划专项（青年人才专项）1项。已在国际核心刊物如Chem. Sci., Org. Lett., Chem. Commun., Org. Chem.Front.等上发表篇SCI论文近20篇。

主持项目:

1. 硅代过氧化物促进的脂肪族碳氢键羟基化反应研究（22001096），国家自然科学基金（青年基金），24万 ，主持；  

2. 可见光催化的糖苷类羟基选择性芳基化反应研究（LQ21B020008），浙江省自然科学基金（探索项目），10 万，主持；

3. 脂肪族碳氢键胺基化反应及其在天然产物结构修饰中的应用研究（2023AY40031），嘉兴市科技计划专项（青年人才专项），15万，主持。

代表论文（近五年）：

1. Kaiting Sun, Tianyi Sun, Yuxin Jiang, Jiayue Shi, Wenlu Sun, Youyou Zheng, Zhixuan Wang, Ziyu Li, Xiaoqing Lv, Xingxian Zhang*, Fan Luo*, Shihui Liu*(通讯作者). Iron-catalyzed benzylic C-H thiolation via photoinduced ligand-to-metal charge-transfer. Chem. Commun., 2024, 60, 5755-5758. (SCI二区, 自然指数期刊)

2. Yuanrui Jiang, Wenjing Zhu, Jiawen Huang, Fan Luo, iaobei Chen, Chunhui Fang, Xin Chen, Shihui Liu*(通讯作者), Yanwei Hu*, Shilei Zhang*. A simple method for N-arylation of secondary amides/amines through a NaH-initiated aryne generation strategy. Org. Chem. Front., 2024, 11, 12-20. (SCI一区, 封面文章) 

3. Bin Shen, Xinyi Feng, Huan Pan, Xiaoqin Zhang, Jiming Wu, Yi He, Ziyue Li, Xiaochun Zou, Zhouqi Lu, Bangwei Zhou, Jing Jin*, Shihui Liu*(通讯作者), Jinlai Gao*. SOX4 as a potential therapeutic target for pathological cardiac hypertrophy. Eur. J. Pharmacol., 2023, 958, 176071. (SCI二区)

4. Tianyi Sun, Ruyi Jin, Yan Yang, Yuqi Jia, Shuxu Hu, Yanqi Jin, Qin Wang, Ziyu Li, Yifan Zhang, Jiming Wu, Yuxin Jiang*, Xiaoqing Lv*, and Shihui Liu*(通讯作者). Direct α-C-H Alkylation of Structurally Diverse Alcohols via Combined Tavaborole and Photoredox Catalysis. Org. Lett., 2022, 24, 7637-7642. (SCI一区, 自然指数期刊)

5. Yifan Zhang, Yuxin Jiang, Yi Wang, Tianyi Sun, Yuanjie Meng, Yueyan Huang, Xiaoqing Lv, Jinlai Gao, Xiaoqin Zhang, Shilei Zhang*, and Shihui Liu*(通讯作者). Photoredox/Copper Dual-Catalyzed Benzylic C-H Esterification via Radical-Polar Crossover. Org. Lett., 2022, 24, 2679-2683. (SCI一区, 自然指数期刊)

6. Xiang Li, Yifan Zhang, Kailin Lu, Shihui Liu*(通讯作者), Yongqiang Zhang*. Aminofluorination-based Structural Modification of Curcumol for the Construction of 3D-Shaped Natural Product Fragment Library. Chin. J. Org. Chem., 2022, 42,  2124-2133. (一级期刊)

7. Tianyi Sun, Yifan Zhang, Yuanjie Meng, Yi Wang, Qifeng Zhu*, Yuxin Jiang*, Shihui Liu*(通讯作者). Photoredox-Copper Dual-catalyzed Site-selective O-alkylation of Glycosides. Chin. J. Org. Chem., 2022, 42, 1414-1422. (一级期刊)

8. Min Dong, Yuqi Jia, Wei Zhou, Jinlai Gao, Xiaoqing Lv, Fan Luo, Yongqiang Zhang*, Shihui Liu*(通讯作者). A Photoredox/Nickel Dual-Catalytic Strategy for Benzylic C-H Alkoxylation. Org. Chem. Front., 2021, 8, 6881-6887. (SCI一区)

9. Yingying Ma, Shihui Liu(共同第一作者), Yifan Xi, Hongrui Li, Kai Yang, Zhihao Cheng, Wei Wang* and Yongqiang Zhang*. Highly Stereoselective Synthesis of Aryl/Heteroaryl-C-Nucleosides via the Merger of Photoredox and Nickel catalysis. Chem. Commun., 2019, 55, 14657-14660. (SCI二区, 自然指数期刊)

10. KaiLin Lu, Yingying, Ma, Shihui Liu, Shixun Guo, Yongqiang Zhang. Highly Stereoselective C-Glycosylation by Photocatalytic Decarboxylative Alkynylation on Anomeric Position: A Facile Access to Alkynyl C-Glycosides. Chin. J. Chem., 2022, 40, 681-686. (SCI一区)

11. Huaqiang Fan, Yi Wan, Peng Pan, Wenbin Cai, Shihui Liu, Chuanxu Liu, Yongqiang Zhang. A cascade approach to 3D cyclic carbamates via an ionic decarboxylative functionalization of olefinic oxamic acids. Chem. Commun., 2020, 56, 86-89. (SCI二区, 自然指数期刊)

12. Jiaqi Guo, Yating Wang, Yuhang Li, Kailin Lu, Shihui Liu, Wei Wang*, Yongqiang Zhang*. Graphitic Carbon Nitride Polymer as a Recyclable Photoredox Catalyst for Decarboxylative Alkynylation of Carboxylic Acids. Adv. Synth. Catal., 2020, 362, 3898-3904. (SCI二区)

授权专利：

1. 刘石惠, 周伟, 李子瑜, 吕晓庆, 高金来. 一种苄基醚类化合物及其合成方法(ZL 2021 1 1040688.2)

获奖情况：

1. 基于金属催化的还原和交叉偶联反应研究及其在药物合成中的应用，中国有色金属工业科学技术奖二等奖，6/8。

2. 新型抗肿瘤药物靶向共递送系统研发及其应用，中国产学研合作创新成果奖二等奖，9/10。

3. 基于纳米递药系统的抗肿瘤靶向协同治疗相关技术研究及应用，全国商业科技进步奖二等奖，9/10。

联系方式：

Email: liushihui12310@zjxu.edu.cn