李维，医学博士，博士后，硕士生导师。2024年获得厦门大学医学院临床检验诊断学博士学位。同年进入中国科学技术大学生物学专业博士后流动站。兼任浙江省生物医学学会委员。长期从事临床检验医疗、教学和科研工作。主持或参与国家自然科学基金、省自然科学基金等课题3项，担任Experimental & Molecular Medicine, Emerg Microbes Infect等杂志审稿人，以第一作者或通讯作者发表SCI论著12篇。主要研究方向：性病病原体的诊断及致病机制研究。

主持项目（近5年）:

1. 浙江省自然科学基金，LQN25H190004，梅毒螺旋体膜蛋白Tp47通过线粒体自噬增加血管内皮细胞通透性介导梅毒螺旋体播散的机制研究

2. 嘉兴市科技计划项目，2025CGZ069，梅毒螺旋体膜蛋白Tp47促进内皮细胞血管生成介导梅毒螺旋体播散的机制研究

代表论文（近5年）：

1. Shen W, Zhou H, Wang W, Li W *. Mendelian randomization study of lipid species reveals causal relationship with syphilis. AMB Express. 2025;15(1):63.

2. Cao JH, Li W *. Unraveling the Epigenetic Landscape of Neurosyphilis: Implications for Diagnosis, Treatment, and Long-term Management. J Infect Dis. 2025; 11: jiaf025.

3. Xie L, Li W, Ye WM, et al. Enhancing Neurosyphilis Diagnosis: Evaluating Novel Biomarkers and Clinical Implementation Challenges. Clin Infect Dis. 2024;78(5):1385-1386.

4. Li W, Luo X, Zheng XQ, et al. Treponema pallidum protein Tp0136 promotes angiogenesis to facilitate the dissemination of Treponema pallidum. Emerg Microbes Infect. 2024;13(1):2382236.

5. Li W, Li QL, Xu QY, et al. Tp47 promoted the phagocytosis of HMC3 cells though autophagy induced by endoplamic reticlum stress. J Eur Acad Dermatol Venereol. 2022;36(11):2224-2234.

6. Li W, Xie L, Li QL, et al. Treponema pallidum membrane protein Tp47 promotes angiogenesis through ROS-induced autophagy. J Eur Acad Dermatol Venereol. 2023;37(3):558-572.

7. Xie L, Li W, Ye WM, et al. Serum Ubiquitin C-Terminal Hydrolase-L1, Glial Fibrillary Acidic Protein, and Neurofilament Light Chain Are Good Entry Points and Biomarker Candidates for Neurosyphilis Diagnosis Among Patients Without Human Immunodeficiency Virus to Avoid Lumbar Puncture. Clin Infect Dis. 2023;77(3):472-479.

8. Xie L, Li W, Zheng XQ, et al. Treponema pallidum membrane protein Tp47 induced autophagy and inhibited cell migration in HMC3 cells via the PI3K/AKT/FOXO1 pathway. J Cell Mol Med. 2023;27(20):3065-3074.

9. Xiao Y, Li W, Li QL, et al. Which Is the Optimum Antigen Concentration for the Venereal Disease Research Laboratory Test of Cerebrospinal Fluid for Neurosyphilis Diagnosis: 10 or 17 μL?. Front Med (Lausanne). 2022; 9:877186.

10. Li W, Zhou X, Cai J, et al. Recombinant Treponema pallidum protein Tp0768 promotes proinflammatory cytokine secretion of macrophages through ER stress and ROS/NF-κB pathway. Appl Microbiol Biotechnol. 2021;105(1):353-366.

11. Li W, Cao T, Luo C, et al. Crosstalk between ER stress, NLRP3 inflammasome, and inflammation. Appl Microbiol Biotechnol. 2020;104(14):6129-6140.

12. Li W, Luo C, Xie X, et al. Identification of key genes and pathways in syphilis combined with diabetes: a bioinformatics study. AMB Express. 2020;10(1):83.

联系方式：

Email: liwei0122lw@163.com